MARVIN E. LEVIN, M.D., F.A.C.P.; LILLIAN RECANT, M.D.
The prediabetic period is that interval between conception and the time the genetically predisposed diabetic develops chemical or clinical evidence of abnormal carbohydrate metabolism. This is not a benign interval. Evidence is rapidly accumulating that during this period the structural changes of microangiopathy are already taking place. Despite this early occurrence of microangiopathy, significant degrees of functional organ impairment in diabetes are rarely seen unless the carbohydrate metabolism has become abnormal. From this point of view, the approach to the problem is twofold: to find the prediabetic, and to find the proper therapy for this stage of the disease so
LEVIN ME, RECANT L. Hormonal and Biochemical Studies in a Diabetic Family. Ann Intern Med. 1967;66:69–76. doi: 10.7326/0003-4819-66-1-69
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Published: Ann Intern Med. 1967;66(1):69-76.
Cardiology, Coronary Risk Factors, Diabetes, Endocrine and Metabolism.
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