E. J. H.
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The recommendation of Lawrence and Klipstein, in their paper in this issue of the ANNALS, that folic acid be given routinely to all pregnant women is supported by data reported recently by Lowenstein, Cantlie, Ramos, and Brunton (1) from Montreal. Of nonanemic pregnant women treated from the twenty-ninth week of gestation or earlier with vitamin-iron preparation lacking folic acid and vitamin B12, 26% developed megaloblastic marrows and 50%, low serum folates by the thirty-eighth week. Of women in the same study given folic acid and vitamin B12 in addition, only 3% developed megaloblastic marrows, and their serum folates rose to
H. EJ. Folate Deficiency and Pregnancy. Ann Intern Med. ;66:235–236. doi: 10.7326/0003-4819-66-1-235
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Published: Ann Intern Med. 1967;66(1):235-236.
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