Bram Rose, M.D., F.A.C.P.
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The nature and significance of immunologic A mechanisms and allergic diseases have been clarified considerably in recent years by the application of newer physicochemical methods. The ragweed system that has been the most extensively studied will be described as a model relative to the three well-defined antibody systems related to it. These are, first of all, reagin of skin sensitizing—and more recently called the homocytotropic antibody—blocking, and hemagglutinating antibodies. Of these, reagin is of prime concern in that it is capable, when combined with an allergen after having been fixed to a cell in the absence of complement, of releasing
Rose B. Immunologic Mechanisms in Allergic Disease.. Ann Intern Med. 1967;66:1026–1027. doi: https://doi.org/10.7326/0003-4819-66-5-1026_4
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Published: Ann Intern Med. 1967;66(5):1026-1027.
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