William M. Schreiber, M.D.; Harold O. Conn, M.D.
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Patients with hepatic disease may have carbohydrate intolerance. We have observed an increased prevalence of diabetes mellitus in patients with cirrhosis of the liver and portal systemic shunting. Preliminary observations indicated that standard oral glucose tolerance tests were impaired (75%) in cirrhosis of the liver.
This investigation was undertaken in an attempt to find the prevalence of diabetes mellitus in cirrhosis and to correlate the rate of portal systemic shunting with abnormal glucose tolerance. Standard oral tests (1.75 g glucose/kg body weight) and intravenous (25 g) were done on consecutive days in proved cirrhotic patients and in ten normal controls
Schreiber WM, Conn HO. Glucose Tolerance in Cirrhosis of the Liver.. Ann Intern Med. ;66:1032. doi: 10.7326/0003-4819-66-5-1032_2
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Published: Ann Intern Med. 1967;66(5):1032.
Gastroenterology/Hepatology, Liver Disease.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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