Hermann Mattenheimer, M.D.
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While micropuncture of the nephron cannot be done in man, studies in other species have indicated the sites of tubular excretion and reabsorption of various substances as reported by other authors. Enzymes in the tubular cells are catalysts in many of the mechanisms underlying the physiological processes of reabsorption from and secretion into the tubular fluid.
The introduction of the percutaneous renal biopsy technique made tissue from human (as well as animal) organs not only available for histological investigation but also accessible for biochemical studies. Methods have been developed in our laboratory to determine quantitatively the biochemical anatomy of the
Mattenheimer H. Enzymatic Aspects of Nephron Function.. Ann Intern Med. ;66:1051–1052. doi: 10.7326/0003-4819-66-5-1051_3
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Published: Ann Intern Med. 1967;66(5):1051-1052.
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