John W. Rebuck, M.D., Ph.D.; Fred W. Whitehouse, M.D., F.A.C.P.; F. Robert Neher, M.D.; Klaus F. Lang, M.D.
This content is PDF only. Please click on the PDF icon to access.
The diabetic is allegedly more susceptible to infection than the nondiabetic. We have studied the local cellular reaction to inflammatory stimuli in the diabetic in an attempt to elucidate this problem.
Using our skin window technique to study the cellular reaction to stress, we performed 76 test lesions in 37 diabetic patients. Local stimuli included insulin (24 lesions), a suspension of killed Escherichia coli (16 lesions), and diphtheria toxoid (36 lesions). Appropriate control studies have been done. The cellular exudate was stained by the Leishman and periodic acid-Schiff (PAS) techniques.
Quantitatively, the cellular response in the diabetic did not differ
Rebuck JW, Whitehouse FW, Neher FR, Lang KF. Local Cellular Faults in Inflammation in the Diabetic—Failure of Glycogen Transport.. Ann Intern Med. ;66:1060–1061. doi: 10.7326/0003-4819-66-5-1060_3
Download citation file:
Published: Ann Intern Med. 1967;66(5):1060-1061.
Cardiology, Coronary Risk Factors, Diabetes, Endocrine and Metabolism.
Copyright © 2019 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use