Gerald T. Perkoff, M.D., F.A.C.P.; Virgil Bleisch, M.D.; George Klinkerfuss, M.D.; Marconi Dioso, M.D.
This content is PDF only. Please click on the PDF icon to access.
Several muscular abnormalities exist in alcoholism. Studies reveal biochemical alterations in asymptomatic alcoholic patients, acute myopathies, and a chronic proximal myopathy. We report here experience with 48 asymptomatic alcoholics, 6 with acute myopathy (1 with gross myoglobinuria, 5 with severe cramps or tenderness or both and weakness) and 10 with chronic myopathy. Transition from acute to chronic myopathy was observed.
Many asymptomatic alcoholics described muscle cramps in the past; 36 out of 48 had elevated serum creatine phosphokinase (CPK). Other changes included abnormal lactic acid responses to ischemic exercise and micromyoglobinuria (detected by immunodiffusion). The patient with gross myoglobinuria and
Perkoff GT, Bleisch V, Klinkerfuss G, Dioso M. Recent Studies of Alcoholic Myopathy, Including Electron Microscopy.. Ann Intern Med. 1967;66:1064. doi: 10.7326/0003-4819-66-5-1064_1
Download citation file:
Published: Ann Intern Med. 1967;66(5):1064.
Tobacco, Alcohol, and Other Substance Abuse.
Results provided by:
Copyright © 2019 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use