MARY M. CARRUTHERS, M.D.; MAHMOOD AKBARI-FARD, M.D.; A. MARTIN LERNER, M.D., F.A.C.P.
The prevalence of all forms of congenital syphilis has declined remarkably in the penicillin era, and only three reports of congenital neurosyphilis have been found in the English literature during the past 5 years (1-4). Paresis is an uncommon manifestation of congenital syphilis and is preventable by penicillin, but once present, it often responds poorly to therapy. However, the disease is not extinct, and the following reminds us that serologic tests for syphilis are still requisite in the pregnant woman and the neonate and that congenital syphilis must be considered when neuropsychiatric manifestations present during childhood or adolescence.
CARRUTHERS MM, AKBARI-FARD M, LERNER AM. A Case of Congenital Paresis in 1966. Ann Intern Med. ;66:1204–1206. doi: 10.7326/0003-4819-66-6-1204
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Published: Ann Intern Med. 1967;66(6):1204-1206.
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