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A symposium honoring Sir Macfarlane Burnet appropriately considers the thymus. These papers by outstanding immunobiologists summarize views of thymic immunologic function as of August 1965. The areas covered include the structure and development of the thymus, immunologic function of the lymphocyte, the role of the thymus in cellular and humoral immunity and in carcinogenesis, and the relationship of the thymus to autoimmune diseases.
Several contributions deserve particular comment. Clark presents convincing evidence that in the mouse thymic medullary epithelial cells secrete sulfated acid mucopolysaccharides, probably the humoral factors regulating immunogenesis. Gowan shows that small lymphocytes may reproduce themselves, may carry
The Thymus: Experimental and Clinical Studies.. Ann Intern Med. 1967;67:223. doi: https://doi.org/10.7326/0003-4819-67-1-223_1
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Published: Ann Intern Med. 1967;67(1):223.
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