Skip Navigation
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 18.208.159.25. If your access is via an institutional subscription, please contact your librarian to request reinstatement. If you are using a personal subscription, please contact the publisher.
Menu
Diagnosis and Treatment |1 August 1967

Extracorporeal Irradiation of the Blood and Lymph in the Treatment of Leukemia and for Immunosuppression

EUGENE P. CRONKITE, M.D.

FULL TEXT

This content is PDF only. Please click on the PDF icon to access.

Abstract

Before one logically can consider perturbation of lymphopoiesis, immunity, or leukemic cell proliferation by killing cells in blood flowing through an extracorporeal radiation field, it is essential to understand the interrelations of blood and lymphatic lymphocytes or leukemic cells to their formative tissues. The notion of perturbing homeostasis in general by physical treatment (cold, radiation, etc.) of the blood flowing through an extracorporeal shunt was first published by Heymans (1) in 1921. However, it was not until a clear pattern of lymphocytic function, migration, and lifespan emerged that development of procedures to deplete the body of lymphocytes (analogous to hemorrhage

FULL TEXT
PDF
Not Available
Citations
Citation

CRONKITE EP. Extracorporeal Irradiation of the Blood and Lymph in the Treatment of Leukemia and for Immunosuppression. Ann Intern Med. 1967;67:415–423. doi: 10.7326/0003-4819-67-2-415

Download citation file:

© 2019

×
Permissions

Published: Ann Intern Med. 1967;67(2):415-423.

DOI: 10.7326/0003-4819-67-2-415

35 Citations

Related Articles
Reactivation of Hepatitis B During Immunosuppressive Therapy: Potentially Fatal Yet Preventable
Annals of Internal Medicine; 156 (10): 743-745
Philadelphia ChromosomePositive Leukemias: From Basic Mechanisms to Molecular Therapeutics
Annals of Internal Medicine; 138 (10): 819-830
Outcome of Pregnancy and Disease Course among Women with Aplastic Anemia Treated with Immunosuppression
Annals of Internal Medicine; 137 (3): 164-172
Pregnancy Outcomes in Women with Aplastic Anemia Treated with Immunosuppression
Annals of Internal Medicine; 137 (3): I-34
View MoreView Less

Related Topics
Hematology/Oncology
Leukemia/Lymphoma

Hematology/Oncology, Leukemia/Lymphoma.

PubMed Articles
Upregulation of microRNA-141 contributes to suppressing epithelial-mesenchymal transition and lymph node metastasis in laryngeal cancer through HOXC6-dependent TGF-β signaling pathway.
Cell Signal 2019.
Clinical investigation of CAR T cells for solid tumors: lessons learned and future directions.
Pharmacol Ther 2019.
View More

Results provided by: PubMed

CONTINUE WITH LIMITED ACCESS
Annals of Internal Medicine
To receive access to the full text of freely available articles, alerts, and more. You will be directed to acponline.org to complete your registration.
×
acp link acp
silverchair link silverchair

Copyright © 2019 American College of Physicians. All Rights Reserved.

Print ISSN: 0003-4819 | Online ISSN: 1539-3704

Privacy Policy

|

Conditions of Use

This site uses cookies. By continuing to use our website, you are agreeing to our privacy policy. | Accept
×

You need a subscription to this content to use this feature.

×
PDF Downloads Require Access to the Full Article.
Annals of Internal Medicine
To receive access to the full text of freely available articles, alerts, and more. You will be directed to acponline.org to complete your registration.
×
Access to this Free Content Requires Users to be Registered and Logged In. Please Choose One of the Following Options
Annals of Internal Medicine
To receive access to the full text of freely available articles, alerts, and more. You will be directed to acponline.org to complete your registration.
×