RICHARD P. O'NEILL, M.D.; JEROME E. COHN, M.D., F.A.C.P.; EDMUND D. PELLEGRINO, M.D., F.A.C.P.
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Pulmonary alveolar microlithiasis is a rare disorder characterized by small calcific concretions in the alveoli. The classical description of the disease was given by Harbitz (1) in 1918, and the presently accepted terminology was suggested in 1933 by Puhr (2). In 1957 Sosman, Dodd, Jones, and Pillmore (3) reported 23 new cases, reviewed 21 cases previously published, and emphasized the tendency of the disease to be familial. Additional cases have been recorded, bringing the total to more than 70 cases.
The present report describes studies of pulmonary physiology and calcium metabolism in three siblings with the disease who were among
O'NEILL RP, COHN JE, PELLEGRINO ED. Pulmonary Alveolar Microlithiasis—A Family Study. Ann Intern Med. ;67:957–967. doi: 10.7326/0003-4819-67-5-957
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Published: Ann Intern Med. 1967;67(5):957-967.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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