J. WELDON BELLVILLE, M.D.
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For more than 75 years researchers have been trying to find a potent, nonaddicting analgesic. The U. S. Food and Drug Administration recently approved one of the first such compounds for clinical use, pentazocine (Talwin⌖, WIN 20,228). This may herald a new era in analgesia if similar compounds can be found to complement pentazocine and give us an effective group of nonaddicting agents to meet the full spectrum of patient needs.
About a decade ago May and Murphy (1) described the first synthesis of benzomorphans. Certain quantitative differences were subsequently observed between the effects of these compounds and morphine, which
BELLVILLE JW. Pentazocine—A Nonaddicting Analgesic. Ann Intern Med. ;67:1114–1115. doi: 10.7326/0003-4819-67-5-1114
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Published: Ann Intern Med. 1967;67(5):1114-1115.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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