L. J. KAGEN
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Myoglobin, the low-molecular weight, heme-containing pigment protein of skeletal muscle, has been found in the urine of patients after a variety of types of muscle injury. In certain patients, as well as in experimental animals, renal damage and death due to renal failure have been the sequel to myoglobinuric states (1-5). In animal experiments this has been true after intravenous injection of myoglobin-containing solutions in the absence of muscle trauma.
Myoglobin has been detected by a variety of chemical and physical methods reviewed recently (6) as well as by the use of antibody techniques (7-12). In general, immunologic methods allow
KAGEN LJ. Immunologic Detection of Myoglobinuria After Cardiac Surgery. Ann Intern Med. 1967;67:1183–1189. doi: https://doi.org/10.7326/0003-4819-67-6-1183
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Published: Ann Intern Med. 1967;67(6):1183-1189.
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