RALPH E. GIANELLY, M.D.; ROBERT H. GOLDMAN, M.D.; BERNARD TREISTER, M.D.; DONALD C. HARRISON, M.D.
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Several studies have indicated that propranolol (1-(isopropylamino)-3-(1-naphthyloxy)-2-propranol) hydrochloride, a beta-adrenergic blocking drug, may be useful in the treatment of angina pectoris. The drug has been reported to reduce the frequency and severity of chest pain and to increase exercise tolerance (1-3). Although it appears that propranolol may be helpful in the management of some patients with angina pectoris, it has been impossible to predict which patients will be helped. A simple test to separate a priori those patients who would respond to propranolol from those who would not would be very valuable to clinicians since the drug may have major
GIANELLY RE, GOLDMAN RH, TREISTER B, HARRISON DC. Propranolol in Patients with Angina Pectoris. Ann Intern Med. 1967;67:1216–1225. doi: 10.7326/0003-4819-67-6-1216
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Published: Ann Intern Med. 1967;67(6):1216-1225.
DOI: 10.7326/0003-4819-67-6-1216
Cardiology, Coronary Heart Disease, Coronary Risk Factors, Hypertension, Nephrology.
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