JOHN R. DURANT, M.D., F.A.C.P.
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The recent excellent conference on leukemia-lymphoma held in Ann Arbor (October 9 to 13, 1967) served again to highlight the complexities in causation of neoplasms. In particular, the discussions of immunologic factors in leukemia-lymphoma by Drs. Osgood, Good, Schwartz, Mellors, and Dameshek emphasized the puzzling role of immunity in oncogenesis. Most physicians readily accept chemicals, viruses, irradiation, and chromosomal damage as oncogenic. It is reasonable to expect immunologic defenses to protect against these influences. However, the observation that thymectomy in mice is protective against leukemo-genesis is most disturbing. Furthermore, the ability of the thymectomized mouse's lymphocytes to develop leukemia is
DURANT JR. Immunology and Cancer. Ann Intern Med. ;68:252–253. doi: 10.7326/0003-4819-68-1-252
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Published: Ann Intern Med. 1968;68(1):252-253.
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