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Two factors have made it difficult for the clinician to assess properly chemotherapeutic agents in the treatment of human disease. First, the tremendous success of the sulfonamides and antibiotics in the management of microbial infections has served as an impetus for the competitive pharmaceutical industry to introduce many "new drugs" for similar purposes. Faced with the array of available drugs, how can the physician select the right agent for a specific patient? Where can he quickly elicit an authoritative statement for his choice? A second factor applicable especially to clinical investigators relates to the stringent Federal regulation on the efficacy
Chemotherapy. An Introductory Text.. Ann Intern Med. ;68:268–269. doi: 10.7326/0003-4819-68-1-268_2
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Published: Ann Intern Med. 1968;68(1):268-269.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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