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Osler's dictum that man has an unlimited craving for drugs stigmatizes one of mankinds greatest obsessions. Meeting this obsession has become a national necessity, an often successful economic enterprise, and a potentially disastrous biological venture. One of the greatest technical hurdles of this game is the impossibility of predicting the clinical usefulness of a drug in humans from experiments performed in other species. In spite of the earlier hopes of "primatologists," the drug responses in our closest congeners are so disappointingly different that one is bound to admit that the "experimentum in corpore vili" has to be performed ultimately in
Drug Responses in Man.. Ann Intern Med. 1968;68:719. doi: https://doi.org/10.7326/0003-4819-68-3-719_1
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Published: Ann Intern Med. 1968;68(3):719.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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