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Obviously, further progress in clinical organ transplantation is still very much dependent upon the exploration of new immunosuppressive methods. Thus it is understandable that since Woodruff's first observation in 1963 that antilymphocytic serum prolonged the survival of rat skin grafts, the attention of investigators has been focused on the serum's ultimate clinical application.
Contributions to the symposium in this volume were made by seven groups whose studies embraced many fundamental and clinical problems. The immunosuppressive efficacy of antilymphocytic serum is clearly confirmed in a variety of in vivo test systems: Positive effects were observed on antibody formation (Woodruff); delayed-type hypersensitivity
Antilymphocytic Serum.. Ann Intern Med. 1968;68:719–720. doi: 10.7326/0003-4819-68-3-719_2
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Published: Ann Intern Med. 1968;68(3):719-720.
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