Yasuo Idezuki, M.D.; John A. Feemster, M.D.; Ronald H. Dietzman, M.D.; Robert Ersek, M.D.; Frederick Goetz, M.D.; Richard C. Lillehei, M.D.
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Two patients with terminal renal failure and severe diabetes mellitus have received combined cadaver kidney and pancreatic duodenal transplants. One patient survived for 4½ months and did not require insulin to maintain the blood glucose in the normal range while the other lived only 3 weeks. This procedure is soundly based on experimental studies in the dog which show that  pancreatectomized dogs can survive for long periods on pancreatic duodenal homografts;  when venous drainage of the pancreatic homograft is into the venous system rather than the portal venous system, there is no adverse effect on the activity of
Idezuki Y, Feemster JA, Dietzman RH, Ersek R, Goetz F, Lillehei RC. Experimental and Clinical Experience with Pancreatic Homotransplantation.. Ann Intern Med. ;68:1148. doi: 10.7326/0003-4819-68-5-1148_1
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Published: Ann Intern Med. 1968;68(5):1148.
Gastroenterology/Hepatology, Pancreatic Disease.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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