Mohamed A. Mobarak, M.D.; Jerome I. Brody, M.D., F.A.C.P.
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This investigation defines the immunochemical features of intralymphocyte antibody proteins as they relate to cell origin, and the age and the state of health of the lymphocyte donor. Tissues used as lymphocyte source were peripheral blood, thymus gland, lymph node, and tonsil, obtained as biopsy or autopsy specimens from healthy individuals and those with lymphoid neoplasms in the following age groups; neonatal, infancy, childhood, pre- and postadolescence, adult maturity, and senescence. Lymphocytes were separated from supporting, mesenchymal, and other extraneous materials and the water-soluble cellular proteins extracted by disrupting thoroughly washed cells with ultrasonic vibration. The clear derivatives were reacted
Mobarak MA, Brody JI. Natural Evolution and Pathological Alterations of Lymphocyte Proteins.. Ann Intern Med. 1968;68:1171. doi: https://doi.org/10.7326/0003-4819-68-5-1171_1
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Published: Ann Intern Med. 1968;68(5):1171.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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