Arthur J. Samuels, M.D., F.A.C.P.; Florence Lepowsky
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Six patients with unequivocal evidence of a hypercoagulable state were studied through one, two, or three complete cycles of exacerbation and remission. Included were patients with  purpura fulminans,  acute leukemia with migratory thrombophlebitis,  anaphylactic reaction after intravenous injection of iron,  prostatic carcinoma,  migratory thrombophlebitis after ingestion of an oral gestagen,  migratory thrombophlebitis, inferior vena cava thrombosis, and pulmonary emboli occurring on two separate occasions, in each instance after 2 weeks of oral gestagen therapy.
Studies included hemoglobin, volume of packed red blood cells, leukocyte count, absolute differential leukocyte count, platelets, clotting time in plastic
Samuels AJ, Lepowsky F. Studies on the Evolution of the Hypercoagulable State in Patients with Thrombotic Diseases.. Ann Intern Med. 1968;68:1172. doi: https://doi.org/10.7326/0003-4819-68-5-1172_1
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Published: Ann Intern Med. 1968;68(5):1172.
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