Norman S. Plummer, F.R.C.P.
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Allergic aspergillosis presents with repeated febrile episodes of collapse and consolidation of the lung, a raised blood eosinophil count, and Aspergillus fumigatus in the sputum. Often characteristic "sputum plugs" are coughed up. Although asthma usually procedes or follows the onset of the disease, it was absent in slightly less than half of my patients.
Immunologic tests are of value, but the only really diagnostic feature is the histological appearance of the bronchial exudate. Fungal filaments are scanty in the inspissated mucus and do not form colonial growths as in other forms of aspergillosis. Silver staining is obligatory.
A study of
Plummer NS. The Diagnosis and Prognosis of Allergic Aspergillosis.. Ann Intern Med. ;68:1175–1176. doi: 10.7326/0003-4819-68-5-1175_4
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Published: Ann Intern Med. 1968;68(5):1175-1176.
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