Catherine J. Condon, M.D.; Richard M. Freeman, M.D.
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We contrasted and compared the clinical picture presented by uremic patients in the predialysis era to that of patients with severe renal failure maintained on hemodialysis. The clinical course and autopsy findings of 25 patients with uremia (group I), hospitalized between 1950 and 1955, were reviewed. Group II included 25 patients of comparable age and degree of renal failure on maintenance hemodialysis since 1964. The classical symptoms of uremia in group I (nausea, vomiting, hiccups, bleeding, seizures, coma) were infrequent or of mild intensity in group II. The following clinical problems, absent or unrecognized in group I, were prominent in
Condon CJ, Freeman RM. The Changing Clinical History of Progressive Renal Failure.. Ann Intern Med. 1968;68:1179. doi: https://doi.org/10.7326/0003-4819-68-5-1179_2
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Published: Ann Intern Med. 1968;68(5):1179.
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