Hiroshi Nagaya, M.D.; C. Edward Buckley III, M.D.; Herbert O. Sieker, M.D., F.A.C.P.
This content is PDF only. Please click on the PDF icon to access.
A high prevalence of rheumatoid factor (RF) has been reported in the serum of patients with idiopathic pulmonary fibrosis. Patients with typical rheumatoid arthritis and high titers of RF often show evidence of diffuse or localized pulmonary disease. Although pulmonary involvement occurs in patients with systemic connective tissue diseases, they rarely present exclusively with bronchopulmonary systems. We have studied eight patients with otherwise uncomplicated chronic lung disease in whom antinuclear factor (ANF) has been demonstrated. Other illnesses commonly associated with ANF were excluded. ANF was assayed by indirect double sandwich fluorescent antibody technique using monospecific goat anti-human immunoglobulin (Ig)G, IgA,
Nagaya H, Buckley CE, Sieker HO. Positive Antinuclear Factor in Patients with Chronic Lung Disease.. Ann Intern Med. 1968;68:1186. doi: 10.7326/0003-4819-68-5-1186_2
Download citation file:
Published: Ann Intern Med. 1968;68(5):1186.
Results provided by:
Copyright © 2019 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use