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The Weinberg genetic proband method studies the prevalence of a disease among the relatives of probands who suffer from it and compares it with the prevalence of the same disease among the relatives of controls. Drs. Leigh and Marley have studied the prevalence of rhinitis and bronchial asthma, of other chest diseases, of urticaria and eczema, psoriasis, herpes zoster, rheumatoid arthritis, epilepsy, migraine, and psychiatric disorders in the families of 55 asthmatic probands, matched with the families of 55 nonasthmatic controls, that is, a total of 1,741 living and deceased individuals drawn from a population of 18,000 patients in two
Bronchial Asthma: A Genetic, Population and Psychiatric Study.. Ann Intern Med. 1968;69:178–179. doi: https://doi.org/10.7326/0003-4819-69-1-178_2
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Published: Ann Intern Med. 1968;69(1):178-179.
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