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The etiologic relationship of viruses to various chronic neurologic disorders in man remains conjectural. Included in this symposium are reviews of chronic central nervous system diseases in animals produced by identifiable virus-like agents (CHINA), such as scrapie, rida, and visna in sheep, and encephalopathy in minks. Mechanisms allowing persistance of agents for long periods before producing disease are discussed.
Reviews of infections with other "slow" viruses (Aleutian mink disease virus and lymphocytic choriomeningitis virus) emphasize a potential importance of immune and autoimmune reactions in the pathogenesis of some chronic nervous system disorders. Gibbs and Gajdusek summarize their successful transmission of
Chronic Infectious Neuropathie Agents (China) and Other Slow Virus Infections.. Ann Intern Med. ;69:182. doi: 10.7326/0003-4819-69-1-182_2
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Published: Ann Intern Med. 1968;69(1):182.
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