RICHARD A. GAMS; JOSEPH A. NEAL; FRED G. CONRAD
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A patient developed lymphadenopathy while receiving diphenylhydantoin therapy that histologically resembled malignant lymphoma. Adenopathy regressed when diphenylhydantoin was discontinued but subsequently recurred as a fatal, malignant lymphoma.
Previous reports of hydantoin-induced lymphadenopathy were reviewed and classified. It was found that no consistent clinical or histologic criteria existed to differentiate benign from malignant lymphoid reactions.
GAMS RA, NEAL JA, CONRAD FG. Hydantoin-Induced Pseudo-Pseudolymphoma. Ann Intern Med. ;69:557–568. doi: 10.7326/0003-4819-69-3-557
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Published: Ann Intern Med. 1968;69(3):557-568.
Hematology/Oncology, Hospital Medicine, Leukemia/Lymphoma.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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