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Knowledge about the group of diseases called "leukemia" has expanded rapidly in the last 20 years. The discovery of effective chemotherapy that permits temporary control of the disease has greatly prolonged the life-span, particularly for children with acute leukemia, and has dramatically altered the clinical course of the disease. In addition to suffering the pathophysiological effects of the disease process itself, virtually every patient wth leukemia receives chemotherapy, which modifies both the progression of the disease and the function of the normal tissues of the host. This alteration in natural history of disease has resulted in recognition of new clinical
Pathology of Leukemia.. Ann Intern Med. ;69:648–649. doi: 10.7326/0003-4819-69-3-648_3
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Published: Ann Intern Med. 1968;69(3):648-649.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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