PAUL J. EDELSON, M.D.
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To the Editor: In a recent NIH Clinical Staff Conference (Ann. Intern. Med. 69: 333, 1968), Dr. Lawrence Chessin provided a quick survey of current concepts of the organization of the immune system that seems to have dislocated some of its focusing ideas. He states, "In man, the central lymphoid organ is the thymus. Thymus-dependent functions have been shown to include those associated with cellbound immunity, while the peripheral lymphoid tissues are associated with the production of circulating antibody." Dr. Chessin has conflated two different organizing principles, both crucial to current immunologic thought. First, a distinction has been made, as
EDELSON PJ. LYMPHOID TISSUE—CENTRAL AND PERIPHERAL. Ann Intern Med. ;69:1076–1077. doi: 10.7326/0003-4819-69-5-1076
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Published: Ann Intern Med. 1968;69(5):1076-1077.
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