GEOBEL A. MARIN, M.D.; MICHAEL L. CLARK, M.B., M.R.C.P.; JOHN R. SENIOR, M.D., F.A.C.P.
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Blood levels and urinary excretion of D-xylose, after a 25-g oral load, were determined in 20 patients with cirrhosis. In all patients blood levels of xylose were above normal, and in 15 patients without ascites the urinary excretion of xylose was normal. In the other five cirrhotic patients with ascites and in two additional patients with ascites due to tuberculous peritonitis, the urinary excretion of xylose was markedly reduced. All of these seven patients with ascites had xylose in the ascitic fluid up to 23 hr. These results indicate that low 5-hr urinary excretion of xylose occurs in subjects with ascites, leading to a false-positive test for malabsorption.
MARIN GA, CLARK ML, SENIOR JR. Distribution of D-Xylose in Sequestered Fluid Resulting in False-Positive Tests for Malabsorption. Ann Intern Med. 1968;69:1155–1162. doi: https://doi.org/10.7326/0003-4819-69-6-1155
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Published: Ann Intern Med. 1968;69(6):1155-1162.
Celiac Disease and Malabsorption, Gastroenterology/Hepatology.
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