GEORGE DUNEA, M.B., M.R.C.P.; ROBERT M. KARK, F.R.C.P., F.A.C.P.; ROBERT LANNIGAN, M.D.; DONALD D'ALESSIO, M.D.; ROBERT C. MUEHRCKE, M.D., F.A.C.P.
Two patients with Brucella suis infection had severe renal involvement. Clinical features included transient azotemia, massive proteinuria, hypertension, and later frequency and dysuria. Renal morphological studies revealed a diffuse interstitial nephritis with focal and local glomerular lesions. In one patient clinical and pathological signs of renal disease persisted for over 3 years, suggesting that brucellosis may be a precursor of chronic renal disease.
DUNEA G, KARK RM, LANNIGAN R, D'ALESSIO D, MUEHRCKE RC. Brucella Nephritis. Ann Intern Med. ;70:783–790. doi: 10.7326/0003-4819-70-4-783
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Published: Ann Intern Med. 1969;70(4):783-790.
Infectious Disease, Nephrology.
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