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Clear thinking about clinical disturbances of acid-base metabolism is only possible on the basis of a firm grasp of some indispensable foundations in chemistry. Clinicians and students have often been intimidated by the seeming complexity of acid-base metabolism and have been discouraged from laying foundations solid enough to give them understanding and the satisfaction that comes from understanding. Dr. Frisell has written a small masterpiece of clear, precise, and concise exposition setting forth the necessary minimum of what in his foreword Dr. William R. Waddell calls "elementary but not simple chemistry."
The biochemistry underlying the maintenance of a normal reaction
Acid-Base Chemistry in Medicine.. Ann Intern Med. 1969;70:879–880. doi: 10.7326/0003-4819-70-4-879_2
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Published: Ann Intern Med. 1969;70(4):879-880.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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