John H. Lawrence, M.D., F.A.C.P.; Cornelius A. Tobias, Ph.D.; John A. Linfoot, M.D., F.A.C.P.; James L. Born, M.D.
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The successful treatment of acromegaly, a disorder related to hyperfunction of the pituitary gland and first described in 1886 by Marie, is still being sought. Long periods of relief of signs and symptoms are not often achieved, and life expectancy is poor. The relative insensitivity of the pituitary gland to externally delivered radiation has long been known, and the end results of treatment with conventional radiation are relatively unsatisfactory. Surgical hypophysectomy, and also pituitary implants using gold-198 or yttrium-90, have recently been used with considerable success. However, without entering the cranial cavity, we now have developed a method for delivering
Lawrence JH, Tobias CA, Linfoot JA, et al. Heavy Particles in Treatment of Acromegaly.. Ann Intern Med. 1969;70:1063. doi: https://doi.org/10.7326/0003-4819-70-5-1063_2
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Published: Ann Intern Med. 1969;70(5):1063.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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