Donald H. Kuiper, M.D.; Daniel J. Fall, M.D.; Bergein F. Overholt, M.D.; H. Marvin Pollard, M.D., F.A.C.P.
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The scientific literature is replete with reports that have attempted to define the effects of aspirin upon the gastrointestinal tract. While some authors have presented evidence for a noxious effect, others have presented data to the contrary. No previous studies have reported fecal blood loss and gastroscopy findings in a group of healthy subjects. A prospective study of 19 healthy male subjects was made in which a correlation of aspirin ingestion, fecal blood loss, blood salicylate levels, prothrombin concentrations, ABO blood groups, and the history of previous salicylate intake was sought. All subjects were studied for 8 days. An initial
Kuiper DH, Fall DJ, Overholt BF, et al. The Effect of Aspirin on Fecal Blood Loss with Gastroscopic Correlation in Healthy Volunteers.. Ann Intern Med. 1969;70:1069. doi: 10.7326/0003-4819-70-5-1069_1
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Published: Ann Intern Med. 1969;70(5):1069.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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