Ediz Z. Ezdinli, M.D.; Avery Sandberg, M.D.; Joseph E. Sokal, M.D., F.A.C.P.
This content is PDF only. Please click on the PDF icon to access.
Chromosomal studies were performed in 76 cases of chronic myelocytic leukemia (initial diagnosis) using a direct technique for examination of bone marrow cells, except for a few cases in which resort to study of cultured peripheral blood cells was necessary. Of the 76 patients, 49 were Ph1-positive. These included 1 whose final clinical diagnosis was myeloblastic leukemia, 1 with erythroleukemia, and 3 with myeloid metaplasia; 44 patients (90%) were classified as having unequivocal chronic myelocytic leukemia. The 27 Ph1-negative patients included 4 whose final diagnosis was myeloblastic leukemia, 2 with eosinophilic leukemia, 1 with myeloid metaplasia, and 2 with leukemoid
Ezdinli EZ, Sandberg A, Sokal JE. Definition of Chronic Myelocytic Leukemia (CML) According to the Ph1 Chromosome.. Ann Intern Med. 1969;70:1083. doi: 10.7326/0003-4819-70-5-1083_1
Download citation file:
Published: Ann Intern Med. 1969;70(5):1083.
Results provided by:
Copyright © 2019 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use