Nathanial F. Pierce, M.D.; John B. Banwell, D.M.; Sherwood I. Gorbach, M.D.; Rupak C. Mitra, M.B.B.S.
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Patients convalescent from acute bacteriologically proved cholera were studied to determine if any became long-term carriers of Vibrio cholerae. Eighty-one patients in early convalescence were given magnesium sulfate purge after three consecutive daily stool cultures had been negative for V. cholerae. Culture of the liquid stool thus obtained was positive in three patients (3.7%). These three were studied repeatedly for 150 to 404 days to determine the duration and bacteriologic characteristics of the convalescent carrier state. These carriers harbored vibrios from 60 to 331 days. During this period routine stool cultures were usually negative (33 to 36 negative); however, vibrios
Pierce NF, Banwell JB, Gorbach SI, Mitra RC. Bacteriologic Studies of Long-Term Convalescent Carriers of Cholera Vibrios.. Ann Intern Med. 1969;70:1091. doi: 10.7326/0003-4819-70-5-1091_2
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Published: Ann Intern Med. 1969;70(5):1091.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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