Paul H. Levine, M.D.; Deborah A. Merrill, M.A.; Peter F. Kohler, M.D.; Henry N. Claman, M.D.
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The relative contributions of humoral and cellmediated immune mechanisms in the rejection of renal homotransplants is an important but still unresolved issue. The diversity of the clinical and pathological pictures in different patients suggests that more than one mechanism may be operating at various times. This study determined serum immunoglobulin levels and complement activity in a series of renal transplant patients and attempted to assess the humoral contribution to rejection. Serial serum samples were obtained from 11 patients receiving renal homografts. Eight patients had clinically apparent episodes of rejection in the first week after surgery, and 3 of these had
Levine PH, Merrill DA, Kohler PF, et al. Changes in Serum Immunoglobulin and Complement Levels Following Renal Homotransplantation.. Ann Intern Med. 1969;70:1095. doi: 10.7326/0003-4819-70-5-1095_1
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Published: Ann Intern Med. 1969;70(5):1095.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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