G. A. Bray, M.D.; J. Londono, M.D.; T. F. Gallagher Jr., M.D.
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Twenty-three obese patients (19 females) had a reduced response to stimuli that usually increase growth hormone. They were studied before and after diethylstilbestrol, weight loss, or triidothyronine, or a combination. Diethylstilbestrol, 5 mg twice a day for 2 days, in four women did not alter their initial, flat growth, hormone response to intravenous arginine. After weight loss ranging from 6 to 60 kg, fasting plasma insulin decreased by an average of 6 µunits/ml, and the postinsulin rise in growth hormone was increased. This increase was directly proportional to the absolute weight loss. Weight loss also augmented the rise in growth
Bray GA, Londono J, Gallagher TF. Effect of Weight Loss and Triiodothyronine on Plasma Growth Hormone and Insulin in Obesity.. Ann Intern Med. 1969;70:1100. doi: https://doi.org/10.7326/0003-4819-70-5-1100_3
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Published: Ann Intern Med. 1969;70(5):1100.
Cardiology, Coronary Risk Factors, Diabetes, Endocrine and Metabolism, Obesity.
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