David J. Kudzma, M.D.; Gustav Schonfeld, M.D.
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One of three mechanisms has generally been invoked to explain the lipemia of ethanol intoxication:  impaired removal of particulate fat due to diminished plasma lipoprotein lipase activity;  increased fatty acid mobilization from adipose to liver; and  enhanced hepatic lipogenesis. We report the first study of sequential changes in lipoproteinemia induced by ethanol in two patients with ethanol-induced hypertriglyceridemia. The data support the last of three mechanisms and assign a contributing role to dietary fat.
Admission hypertriglyceridemia disappeared in both cases on a high carbohydrate diet (65% carbohydrate, 25% fat). (Corn oil was the sole source of fat
Kudzma DJ, Schonfeld G. Ethanol-Induced Hypertriglyceridemia.. Ann Intern Med. ;70:1101–1102. doi: 10.7326/0003-4819-70-5-1101_3
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Published: Ann Intern Med. 1969;70(5):1101-1102.
Cardiology, Coronary Risk Factors, Dyslipidemia.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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