Charles E. Jackson, M.D., F.A.C.P.; Joseph D. Mann, M.D.
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The 1962 report of the discovery of a sex-linked A blood group system, termed Xga, has been a recent stimulus to the study of X-linked inheritance in man. This presentation reviews the contributions of this system to medical science and discusses its proposed interaction with the male-to-female birth ratio.
Family studies of Xga by numerous investigators have permitted the mapping of the X chromosome for genes for muscular dystrophy, hemophilia, color blindness, and many other conditions in relationship to the Xga marker gene. Xga studies in Klinefelter's and Turner's syndromes have permitted the tracing of the parental origin of the
Jackson CE, Mann JD. Contributions of the Xga Blood Group System to Medicine.. Ann Intern Med. 1969;70:1107–1108. doi: https://doi.org/10.7326/0003-4819-70-5-1107_2
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Published: Ann Intern Med. 1969;70(5):1107-1108.
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