H. ROYDEN JONES JR., M.D.; ROBERT G. SIEKERT, M.D.; JOSEPH E. GERACI, M.D.
Twenty-nine percent of patients (110 of 385) with bacterial endocarditis had neurologic involvement. In 60% (65 of 110 patients) the neurologic finding was either the chief complaint or one of the major presenting symptoms. Cerebrovascular lesions accounted for 50% (55 of 110) of the cases, and transient ischemic symptoms preceded the major stroke in 15 of the 55 (27%).
Other major neurologic syndromes included toxic encephalopathy, meningitis, organic headache, mononeuritis, convulsions, and visual impairment. Occasionally, the initial diagnosis was not bacterial endocarditis but a primary neurologic illness or some other systemic disease. The mortality rate of 50% (55 of 110 patients) was 1.6 times greater than that expected in a general series of patients with endocarditis.
JONES HR, SIEKERT RG, GERACI JE. Neurologic Manifestations of Bacterial Endocarditis. Ann Intern Med. 1969;71:21–28. doi: 10.7326/0003-4819-71-1-21
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Published: Ann Intern Med. 1969;71(1):21-28.
Cardiology, Endocarditis, Infectious Disease.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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