LAWRENCE GOULD, M.D., F.A.C.P.; MOHAMMAD ZAHIR, M.D.; MAHMOOD SHARIFF, M.D.; MARY DILIETO, B.A.
Fifteen male patients with a long history of alcoholic intake underwent cardiac catheterization. At the time of the study the patients had been hospitalized for at least several weeks and were receiving nutritious diets. Clinically, all of the patients had normal cardiovascular findings and minimal or no liver disease. Six patients were found to have a high resting cardiac output, and nine patients were found to have a normal resting cardiac output. All of the patients had normal resting cardiac pressures. On exercise 13 of the patients showed a significant increase in the left ventricular end-diastolic pressure and mean pulmonary artery pressure. Further, five of the patients showed a fall in the stroke index on exercise. This abnormal exercise response, in chronic alcoholic patients without significant liver disease, indicates the presence of an impairment in cardiac function.
GOULD L, ZAHIR M, SHARIFF M, et al. Cardiac Hemodynamics in Alcoholic Heart Disease. Ann Intern Med. 1969;71:543–549. doi: 10.7326/0003-4819-71-3-543
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Published: Ann Intern Med. 1969;71(3):543-549.
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