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Case Reports |1 September 1969

Agammaglobulinemia and Regional Enteritis

RONALD C. EGGERT, M.D.; I. DODD WILSON, M.D.; ROBERT A. GOOD, M.D., PH.D.

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  • Minneapolis, Minnesota
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Abstract

An 18-year-old white man with congenital agammaglobulinemia that was probably sex-linked developed clinically and pathologically typical regional enteritis. The association of these diseases provides evidence that antibody is not directly involved in the pathogenesis of regional enteritis and that plasma cells, a usual histologic feature of regional enteritis, are not essential. Antibody lack probably does not predispose to regional enteritis, and cellular immunity may be important in its pathogenesis.

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EGGERT RC, WILSON ID, GOOD RA. Agammaglobulinemia and Regional Enteritis. Ann Intern Med. 1969;71:581–585. doi: https://doi.org/10.7326/0003-4819-71-3-581

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Published: Ann Intern Med. 1969;71(3):581-585.

DOI: 10.7326/0003-4819-71-3-581

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