MORDEKHAI MORITZ, M.D., F.A.C.P.; PAUL C. KAHN, M.D.; ALLAN D. CALLOW, PH.D., M.D., F.A.C.S.; RUVEN LEVITAN, M.D., F.A.C.P.
A patient with Zollinger-Ellison syndrome is presented in whom diarrhea and steatorrhea were the major clinical manifestations. The diarrhea disappeared rapidly when the patient was put on a gluten-free diet. An increased skin pigmentation that appeared later was associated with elevated serum level of beta-melanocyte-stimulating hormone (beta-MSH). Extract of the pancreatic tumor showed no activity of beta-MSH or adrenocorticotrophic hormone. Hitherto undescribed angiographic features of the arteries supplying the stomach were observed. The possibility that these findings were related to gastric acid hypersecretion is discussed.
MORITZ M, KAHN PC, CALLOW AD, et al. Unusual Clinical Manifestations and Angiographic Findings in a Patient with the Zollinger-Ellison Syndrome. Ann Intern Med. 1969;71:1133–1140. doi: 10.7326/0003-4819-71-6-1133
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Published: Ann Intern Med. 1969;71(6):1133-1140.
Endocrine and Metabolism, Endocrine Cancer, Gastroenterology/Hepatology, Hematology/Oncology, Peptic Disease.
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