DOUGLAS N. GOLDING, M.D., F.R.C.P.I.
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To the Editor: I was interested in the correspondence on the subject of rheumatoid arthritis (R.A.) cells (Ann. Intern. Med., 10: 432, 1969). We have always considered that demonstration of rheumatoid factor liberated from exudative vacuolated leukocytes (granular white cells containing cytoplasmic inclusions) after washing and disintegration of these cells was essential for their identification as R.A. cells. For example, this criterion was fulfilled when these cells were demonstrated in the pleural fluid in a case of rheumatoid pleural effusion (1).
It would seem to me that vacuolated leukocytes in exudative fluids might raise suspicion of rheumatoid disease, but that
GOLDING DN. RHEUMATOID ARTHRITIS CELLS. Ann Intern Med. ;71:1216. doi: 10.7326/0003-4819-71-6-1216_1
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Published: Ann Intern Med. 1969;71(6):1216.
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