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This annual work, which critically reviews various aspects of medical genetics, has been increased in size in this volume with seven competent contributors. "Chromosomal Abnormalities in Clinical Medicine" by D. H. Carr provides a most helpful discussion updating information on significant advances in this rapidly moving field. The complexity of the sex chromosomal abnormalities including frequency estimates are carefully collated and discussed here. The mechanisms of loss and recombination of chromosomal material are carefully presented with the clear implication that such phenomena as inversions, small deletions, and translocations may be frequent although as yet undetected. R. B. McConnell presents an
Progress in Medical Genetics.. Ann Intern Med. 1970;72:445–446. doi: https://doi.org/10.7326/0003-4819-72-3-445_3
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Published: Ann Intern Med. 1970;72(3):445-446.
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