SIDNEY J. FILLMORE, M.D.; MARIO SHAPIRO, M.D.; THOMAS KILLIP, M.D., F.A.C.P.
The present study documents by serial blood gas measurements that temporary support of the arrested circulation is more likely to be effective when prompt ventilation and endotracheal intubation are performed. Intubation is associated with lower arterial PCO2 and higher oxyhemoglobin saturation. When arterial PCO2 is near normal, bicarbonate is more effective in normalizing blood pH. Even when normal blood pH is achieved, extremely high blood lactate values may be present. Unsatisfactory blood gas values occurring in intubated, vigorously breathed patients probably reflect impairment of gas exchange due to fluid-filled lungs. Serial blood gas studies have proved useful in understanding and testing the physiologic consequences of cardiopulmonary arrest.
FILLMORE SJ, SHAPIRO M, KILLIP T. Serial Blood Gas Studies During Cardiopulmonary Resuscitation. Ann Intern Med. 1970;72:465–469. doi: 10.7326/0003-4819-72-4-465
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Published: Ann Intern Med. 1970;72(4):465-469.
Emergency Medicine, Pulmonary/Critical Care.
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