GLENN A. LANGER, M.D.; ALLAN J. BRADY, Ph.D.; KENNETH I. SHINE, M.D.; JOY A. SOPIS, Ph.D.
Certain aspects of cardiac function as related to the normal and diseased heart are summarized. Topics discussed include:  myocardial ultrastructuralfunctional relationships;  the process of electrical excitation and conduction and the basic physiology of arrhythmias and conduction defects;  methods of evaluation of myocardial failure in the patient and present concepts of the cellular basis of heart failure; and  the role of the ions in the control of the myocardial contractile process and the possible relationships between ionic flux and digitalis action.
LANGER GA, BRADY AJ, SHINE KI, et al. Cardiac Disease and Its Treatment—Some
Physiological Correlations. Ann Intern Med. 1970;72:715–727. doi: https://doi.org/10.7326/0003-4819-72-5-715
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Published: Ann Intern Med. 1970;72(5):715-727.
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