William J. Grace, M.D., F.A.C.P.; Richard J. Kennedy, M.D., F.A.C.P.; John A. Chadbourn, M.D.
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It is commonly believed that patients with acute myocardial infarction or impending myocardial infarction may have a perfectly normal ECG when first examined so that patients with a normal ECG are frequently hospitalized on the basis of a history of chest pain alone. To study this concept the hospital records of 200 consecutive patients with proved acute myocardial infarction were studied. Diagnosis was established by the typical ECG appearance of diagnostic Q waves, sequential T wave changes and elevated (2X) enzymes. Autopsy was performed in 44% of persons who died. Seventy-five percent of the patients had an ECG within 6
Grace WJ, Kennedy RJ, Chadbourn JA. The Time of the First Abnormal Electrocardiogram in Patients with Acute Myocardial Infarction.. Ann Intern Med. 1970;72:780. doi: https://doi.org/10.7326/0003-4819-72-5-780_2
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Published: Ann Intern Med. 1970;72(5):780.
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