James J. Morris Jr., M.D., F.A.C.P.; Abe Walston, M.D.; Robert H. Peter, M.D.; Victor S. Behar, M.D.; Yihong Kong, M.D.
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The pulmonary artery pressure in some patients with mitral stenosis may be elevated out of proportion to the rise in left arterial pressure. This elevation, indicating an increase in pulmonary arteriolar resistance, has been traditionally regarded as a "protective reflex constriction" of the pulmonary arterioles. The danger in accepting this as a reflex mechanism is that other causes may be overlooked. The prevalence and specific cause for an increased pulmonary arteriolar resistance was investigated in a series of 117 patients with hemodynamically pure mitral stenosis.
Complete right- and left-heart catheterizations were performed in all patients and resistance was calculated from
Morris JJ, Walston A, Peter RH, et al. The Implications of Increased Pulmonary Arterial Resistance in Mitral Stenosis.. Ann Intern Med. 1970;72:782. doi: https://doi.org/10.7326/0003-4819-72-5-782_2
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Published: Ann Intern Med. 1970;72(5):782.
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